Brian D. Keppler, Ph.D.

Brian joined McKee, Voorhees & Sease in 2016 after obtaining his PhD in Cellular and Molecular Biology from the University of Wisconsin-Madison. Previously, he received his Master’s degree in Plant Biology and undergraduate degree in Biochemistry, both from Ohio University.

Brian has extensive research experience in the field of plant molecular biology including doctoral research focused on the molecular basis of plant disease resistance.

As a registered Patent Agent, Brian provides support to patent prosecution in the biotechnology and chemical arts.

  • Biotechnology Patents
  • Chemical Patents
  • Academic Research and Technology Transfer
  • Agritech
  • Animal Health
  • Pharma and Nutra
  • Plant Breeding and Plant-Related Technology

Education

University of Wisconsin-Madison, Ph.D., Cellular and Molecular Biology

Ohio University, M.S., Plant Biology

Ohio University, B.S., Biochemistry

Publications & Presentations

Keppler BD, Song J, Nyman J, Voigt CA, Bent AF (2018) 3-Aminobenzamide Blocks MAMP-Induced Callose Deposition Independently of Its Poly(ADP-ribosyl)ation Inhibiting Activity. Front Plant Sci. 9:1907.

Briggs AG, Adams-Phillips LC, Keppler BD, Zebell SG, Arend KC, Apfelbaum AA, Smith JA, Bent AF (2017) A Transcriptomics Approach Uncovers Novel Roles for Poly(ADP-ribosyl)ation in the Basal Defense Response in Arabidopsis thaliana. PLoS One. 12(12):e0190268.

Showalter AM, Keppler BD, Liu X, Lichtenberg J, Welch LR (2016) Bioinformatic Identification and Analysis of Hydroxyproline-Rich Glycoproteins in Populus trichocarpa. BMC Plant Biol 16(1):229.

Song J, Keppler BD, Wise RR, Bent AF (2015) PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses. PLoS Genet 11(5):e1005200.

Keppler BD, Showalter AM (2010) IRX14 and IRX14-LIKE, Two Glycosyl Transferases Involved in Glucuronoxylan Biosynthesis and Drought Tolerance in Arabidopsis. Mol Plant 3(5): 834–841.

Showalter AM, Keppler BD, Lichtenberg J, Gu D, Welch LR (2010) A Bioinformatics Approach to the Identification, Classification, and Analysis of Hydroxyproline-Rich Glycoproteins. Plant Physiol 153(2): 485–513.

Bar & Court Admissions

United States Patent and Trademark Office, 2018

Proposed rulemaking to implement WIPO Standard ST.26

Patent applications containing nucleic acid or protein sequences will be required to submit a sequence listing in compliance with the new WIPO Standard ST.26 beginning on January 1, 2022. With the implementation of the new standard coming soon, the USPTO has issued a notice of proposed rulemaking to revise the rules of practice for submitting […]

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Oatly – wow no cow, yes patents

Oatly, the Swedish oat milk company, has been in the news recently with their initial public offering occurring just last month. Initially priced at $17, shares jumped to $22 on the first day of trading and have been as high as $29 since (which equates to a market cap of over $17 billion!). In the […]

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Deposit of biological material and the differing national laws

For patent applications in the biotechnology area, a biological material is sometimes essential for carrying out the invention. The biological material can be any material capable of reproducing itself or being reproduced in a biological system, including bacteria, fungi, algae, eukaryotic cells, cell lines, hybridomas, plasmids, viruses, and plant seeds. If the biological material cannot […]

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Breakthrough in Protein Structure Prediction

Knowing the three-dimensional structure of a particular protein is critical in determining its function and has implications for everything from treating human disease to herbicide resistant plants. Researchers currently use experimental techniques such as x-ray crystallography, nuclear magnetic resonance, or cryo-electron microscopy to establish the structure. However, these techniques are time consuming and can take […]

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New Grape Varieties – Raisin Awareness of Plant Patents

You may have noticed more options for grapes at your local grocery store in recent years. In addition to the typical red, black, and green grapes that have always been available, there are now unusual shapes and unique flavors including those grapes that that taste like cotton candy! But have you thought about how these […]

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